Some (ongoing) research conducted by Southampton University which has followed several hundred children from birth, turns up some further interesting epigenetic effects - and it is bad news for Low Carb,
- "The Southampton studies have shown clearly that birthweight is not the most important factor in setting the risk of chronic disease. The thickness of the carotid artery of a child at nine years of age, an early and highly objective marker of risk of cardiovascular disease, was statistically related to low carbohydrate intake by the mother in late pregnancy, and this factor was independent of the child's birthweight."
- "In the early 1950s, a doctor in Motherwell in southern Scotland made substantial recommendations about the diet that his women patients should eat during pregnancy. The offspring were studied until they were 30...[Southampton University researchers] analysed how fat these 30-year-olds were from the point of view of whether they were first-born or not...those who were first-born have about 25 percent more body fat than those who were second or subsequent children. More recently, data from Cesar Victora's group in Brazil have shown that first-born children are more likely to have higher blood pressure later."
- "In our first study we found that the degree of epigenetic change measured at birth in one particular gene, associated with the control of fat metabolism, explained about 25 per cent of the differences in body fat between children nine years later"
Gut flora is another theme explored in the book,
- "Generally these bugs inside our bodies are very useful. They help by predigesting our food and play a major role in determining our nutrition and our metabolic health. We know that people with diabetes have different patterns of gut bacteria. We also know that how we develop this internal family of gut bacteria influences whether we get allergies..."