The New York Times has a great article 'Exercise as Housecleaning for the Body':
- "It’s long been known that cells accumulate flotsam from the wear and tear of everyday living. Broken or misshapen proteins, shreds of cellular membranes, invasive viruses or bacteria, and worn-out, broken-down cellular components, like aged mitochondria, the tiny organelles within cells that produce energy, form a kind of trash heap inside the cell.In most instances, cells diligently sweep away this debris. They even recycle it for fuel. Through a process with the expressive name of autophagy, or “self-eating,” cells create specialized membranes that engulf junk in the cell’s cytoplasm and carry it to a part of the cell known as the lysosome, where the trash is broken apart and then burned by the cell for energy.Without this efficient system, cells could become choked with trash and malfunction or die."
Two triggers were identified that lead to autophagy,
- "In petri dishes, the rate of autophagy increases when cells are starved or otherwise placed under physiological stress."
The benefits of cellular autophagy are available to us RIGHT NOW,
"Still, it’s possible that at some point, autophagy-prompting drugs or specialized exercise programs might help everyone to fully benefit from exercise."
Skip a meal here and there (IF), exercise in short sharp burst (power law)....or wait for the pill! ;)